All-in-One CTMS Software

One Clinical Trial Management System for clinical development process and beyond. Evidence-based decisions. More information – less efforts.

Product sheet PDF

ISO 9001-2015 label certification new version

Automate your routine CRA tasks with CRA Activity Management

Create confirmation and follow-up letters in one click with all flexible smart trackers added automatically.
Configure Site Visit Report workflow with electronic signatures to replicate your exact processes.
Poor internet connection at site? Use offline reporting capabilities of the system.

Product sheet PDF

Site Health report

Visit cabinet

Visit calendar

Track what is going on at sites with CTMS Subject Tracking & Invoicing

Have all the information you need in one place: enrollment, inclusion curve, in and out of time window visits, screen failures and so much more.
Use flexible and exportable widgets, reports, and graphs.
Set, measure, organize, and track site payments.

Product sheet PDF

Dashboard

Invoices

Site Budgets

Organize all information on investigators and sites with Investigators & Sites Management

Have sites statuses, documents, contracts, qualification, vendors, timelines and so much more at hand.
Keep all your Medical Institutions and Sites information in a clear organized manner with just a few clicks.
Manage submission packages across countries, studies, and sites in a unified interface.

Product sheet PDF

Site Team

Site Card

Submissions List

Features of Flex Databases CTMS

Site visit planning and scheduling: Pre-Study, Site Initiation, Interim Monitoring, Monitoring Visits, Close-Out, and any other type
Study role-based permissions
Automated notifications and alerts based on various parameters
Assessment metrics creation and CRA performance assessment
Business Intelligence reporting – ANY report is possible
Customizable fields & trackers – all fields in monitoring section can be changed by user at no extra fee
Offline Site Visit Reports – you no longer depend on internet connection at sites
API for integrations – full integration with TMF, EDC systems
Sponsor step: enable optional sponsor step in the workflow to allow sponsor review and sign reports

Centralized calendar and personalized calendars of planned visits
Electronic signature
Monitoring Visits reports, confirmation & follow-up letters generated automatically on customers templates
All trackers are completely flexible and configurable – action items, issues, deviations, subjects enrollment and any other logs
Template designer for all documents – full flexibility with confirmation letters, follow-up letters, site visits reports and questionnaires
Site visits workflows are flexible and can be configured to reflect customer’s exact process
Ad-hoc reporting tool for cross-project and cross-module reporting – graphs, widgets, pies, grids – all exportable

Create study and multi-currency site budgets
Set up any payment rules with overhead percentage, cost and extra cost reductions
Copy budget template to speed up trial set-up
Track non-visit related activities (PTC management)
Manage open queries resolution
Plan and schedule patients visits
Import data from your EDC system or add subjects manually
Generate invoices & beneficiaries on configurable client-specific or ready- to-use templates
Void or approve invoices online

Invoice based on various triggers: visit, procedures, milestones, etc.
Keep different site budget versions and invoice according to specific version
Export and report any data on invoicing into sites
Track unscheduled visits and procedures
Plan enrollment and compare with the real picture
Track all patient related data
Get overall reports on ready to be invoiced, approved and paid activities
Track invoices status

Feasibility process
Site performance
Centralized IRB/LEC submissions and approval tracking
Investigators, sites, hospitals and out-patient clinics, vendor and regulatory authorities information

Site team assignment
Capturing and tracking of all site communication
Documents tracking (contracts, site regulatory documents, licenses and certificates)
Reports

What They Say About Us

Tameo Kobayashi

Chief Innovation Officer, Director, Business Innovation Dept., CMIC HOLDINGS Co., Ltd.

Flex Databases system is very flexible and user friendly. In addition, most importantly the team have much much flexible ways of thinking! I am very proud that we did choose Flex Databases as our platform in CMIC APAC offices.

Joshua Baisley, H.B.Sc.

VP, Clinical Design and Delivery

As we have begun the installation process for Flex Databases system for use with the Clinical Trial Management group, the team at Flex Databases have made this process efficient and organized along with answering any questions that come up internally and jumping on additional meetings with our team to ensure that everything is understood throughout the set up and training process.

Craig Winter

CIO, Agenus Inc.

I have been with Agenus for over 26 years. Over those 26 years, our Flex CTMS and TMF implementation is the smoothest and fastest implementation of a validated IT system we have done.

Cheryl Marron

Manager Clinical Operations

We were searching for a flexible yet straightforward eTMF solution for one of our biotech clients. We have been working with Flex Databases for our internal project management and budgeting and their eTMF solution also convinced us. The Flex Databases team was incredibly helpful with setting the system up in no time.

Ulrike Schorr-Neufing

Director Personnel & Qualification

We have been using Flex Databases software for about 2.5 years now. One major advantage of Flex Databases CTMS is the ability to create specific reports ourselves. Additionally, we value that our feature requests are taken seriously by Flex Databases and added to their development roadmap. We also benefit from their customer-specific configuration service.

Martin Krauss

Director of FGK Clinical Research

FGK selected Flex Databases for CTMS and TMF due to clear structure, intuitive interface, flexible investigator payment module, offline access for CRAs, and positive cooperation with the Flex Databases’ team.

Simon Rückinger

Managing Director at Metronomia Clinical Research GmbH

We were searching for a flexible yet straightforward eTMF solution for one of our biotech clients. We have been working with Flex Databases for our internal project management and budgeting and their eTMF solution also convinced us. The Flex Databases team was incredibly helpful with setting the system up in no time.

Lídice Vidal

Chief Clinical Օperations Officer

We have made a journey of almost two years now, since we were exploring new vendors to change our CTMS system in May 2022, until the deployment of the system last March 2024. It would not be possible without the kind and patient support of Flex team! All the team we have encountered during this time have listened attentively to our needs and doubts, have perfectly understood them, and have always provided us with new options and possible solutions.

Have questions?

Drop us a line and we be happy to answer all your questions

100+

Clients

20 000+

Daily users

10M+

Documents

2 000+

Clinical trials

30+

Countries

CTMS Blog

July 16, 2026

Customize CTMS Dashboards for Every User

Every clinical trial role requires different information. CRAs need to track upcoming monitoring visits, Project Managers need study performance metrics, and clinical operations teams need enrollment and site activity data. In this video, see how Flex Databases CTMS allows every user to create a personalized dashboard without affecting other users. Learn how to add or […]

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June 24, 2026

Investigator Site File Management with Flex Databases

Managing Investigator Site Files across multiple sites is one of the more operationally demanding aspects of clinical trial oversight. Flex Databases addresses this with a dedicated ISF module built around three distinct user experiences (Sponsor, CRA, and Site) each tailored to the workflows and priorities of its audience. The Sponsor View: Study-Wide Visibility Sponsors access […]

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May 26, 2026

Looking for an Enterprise eClinical Solution? There Is More to Consider

When evaluating core clinical research platforms, most companies naturally start with the well-known enterprise brands. They are recognizable, widely adopted, and often positioned as the “safe choice” for regulated environments. But once the demo phase is over and implementation actually begins, many teams discover that choosing a platform involves much more than brand recognition and […]

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May 19, 2026

Clinical Trials Management Software: Key Features for CROs

CROs work in a fast-moving and highly complex environment. They manage multiple studies at the same time, often for different sponsors, across different countries, sites, and timelines. Each study comes with its own processes, reporting needs, and regulatory expectations. As this complexity grows, it becomes harder to keep everything aligned using separate tools or spreadsheets […]

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We are here for all of your questions! Tell us more about yourself and we will organize a tailored live demo to show how you can power up your clinical trials processes with Flex Databases.